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It is in fact possible to greatly simplify the analysis by considering that equations (4), when combined with equation (1), result in a representation of the transition equations which is mathematically equivalent to the classical two-locus model of viability selection and random mating (random fusion of gametes).
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Although it was not a primary goal, this update also improves the accuracy of model prediction of viability and auxotrophy phenotypes and increases the number of epistatic interactions.
This update also improves the accuracy of model prediction of viability and auxotrophy phenotypes and increases the number of epistatic interactions.
We argue that, even though the proportion of parameter-state space allowing multiallele polymorphism is greater under maternal selection than under the standard model of constant viability selection, the former is, in fact, less likely to maintain large numbers of alleles.
Other recent studies favorably related the Living Planet Index's underlying metric (geometric mean abundance) to models of species viability from ecological theory (13) and explored its mathematical properties (14), showing it to be suitable for measuring trends in species extinction risk.
Here, we build off an existing model of differential zygotic viability to incorporate a heterozygosity maintenance term for plant recombinant inbred populations and find a new solution for the genotype probabilities used to calculate recombination frequencies.
In this model, the viability of cells exposed to 200 µM H2O2 for 2 hr was about 50% compared to controls without H2O2 exposure.
Existing methods to model the viability of each genotype differentially treats each marker pair, and so may suffer from the overfitting of large data sets without specific biological models; these have also only been shown for BC1 and F2 populations (Lorieux et al. 1995a, b; Zhu et al. 2007).
In contrast to the Drosophila CG model, the viability of mice deficient in GALT activity and reared on a high-galactose diet is reportedly unaffected, despite the accumulation of very high gal-1-P levels (Leslie et al., 1996; Ning et al., 2001).
We propose a model for this unusual pattern of viability based on the inability of sgs1 mutants to untangle intertwined chromosomes.
Here we introduce a spatial model of evolution which assumes viability selection, mutations and random mating.
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