Sentence examples for model of tuberculosis from inspiring English sources

A selected PDKA compound demonstrated efficacy in a mouse model of tuberculosis.

Its immunogenicity and protective efficacy as well as therapeutic effect were assessed in a mouse model of tuberculosis.

In the second step, plasmids were selected for their ability to induce protective immunity in a mouse model of tuberculosis following DNA immunization.

This paper deals with the problem of optimal control of a deterministic model of tuberculosis (abbreviated as TB for tubercle bacillus).

We discuss here the observation that the distribution and progression of lung and lymph node lesions in the guinea pig aerosol model of tuberculosis have considerable similarity to the naturally occurring disease in children.

Together, these studies reveal an in vitro in vivo relationship of the 2,5,6-trisubstituted benzimidazoles that serves as a criterion for advancing this class of cell division inhibitors into more resource intensive in vivo efficacy models such as the long-term murine model of tuberculosis and Pre-IND PK/PD studies.

This chapter reviews murine and guinea pig models of tuberculosis.

SB-P3G2 and SB-P1G10 were assessed in acute short-term animal models of tuberculosis, which showed that SB-P3G2 demonstrated activity against M. tuberculosis.

Although there are several varieties of animal models of tuberculosis, the mouse and the guinea pig are by far the most validated and useful.

Secondly, we point out that some mouse models of tuberculosis in laboratories in developing countries, where exposure to environmental mycobacteria is large, mimic neglected aspects of human disease more closely than do low-dose infections in hyper-susceptible immunologically naïve mice in the USA or Europe.

Mathematical models of tuberculosis have contributed to the understanding of tuberculosis epidemics and the potential impact of control strategies (see, for example, [7 23]).