Sentence examples for model of toxicity from inspiring English sources

Risk assessment of fluctuating concentrations requires assessment of toxicity over time (prediction of toxic effects beyond test conditions), and such a prediction requires a mechanistic model of toxicity.

Based on this preliminary data, we are able to construct roughly a theoretical predictive model of toxicity based on network response.

However, at this model of toxicity silymarin had better cytoprotective effects compared to saponarin.

These findings led us to propose a two-stage model of toxicity.

Second, narcotic modes of action are, by definition, additive, and an additive model of toxicity does not fit our data.

The CPPs combined information within assays and cell lines using a robust two-stage hierarchical model of toxicity.

Other approaches to sorting gene expression data for toxicogenomics have included several "unsupervised" methods, in which modeling programs search for patterns within data and generate models of toxicity without being given any hint as to what kinds of expression patterns the researchers expect to find.

In vivo and in silico models of toxicity were combined to test the contribution of individual mechanisms and reveal the multi-modal role played by the cardiotonic and scavenging actions of the triglyceride suspension.

Numerous studies have demonstrated that resveratrol show potent protective effects in various models of toxicity [13], [16], [20] including toxicity induced by NO releasing SNP [16].

However, the presence of EAST-1 in EAEC 17-2, a strain which did not cause diarrhea in volunteers, suggests that EAST-1 is not the sole mediator of diarrhea, an observation confirmed by studies which demonstrated EAST-1 from EAEC 17-2 had identical activities to EAST-1 derived from EAEC 042 in in vitro models of toxicity [7], [97].

Traditional models of toxicity have relied on dissecting chemical action into pharmacokinetic and pharmacodynamic processes.