Distal hypoxic stroke: a new mouse model of stroke with high throughput, low variability and a quantifiable functional deficit.
We tested the hypothesis in a rat model of stroke and reperfusion injury.
FAIR-MRI provides repetitive quantitative measurements of hemispheric CBF in a mouse model of stroke.
Kim, H.J. et al. Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action.
In this study, we investigated the effect of hNT cells in a model of stroke in which the striatum remains intact and damage is restricted to the cortex.
We have been addressing this issue by including hyperlipidemia and diabetes, prevalent co-morbid conditions, in our experimental model of stroke.
We examined a battery of behavioral tests to evaluate functional recovery in an aging murine model of stroke.
We therefore examined whether pure PcTx1 is neuroprotective in a conscious model of stroke via direct inhibition of ASIC1a.
Furthermore, cerebral infarct volume in a model of stroke is decreased in whole body SCOP/PHLPP1 KOs 24 h post-injury vs. WTs, and neuroprotection is reversed by co-administration of an AKT inhibitor10.
We found that this new distal hypoxic (DH) model of stroke generates a lesion with a volume of 25% of the ipsilateral hemisphere, extends to the motor cortex and causes a behavioral deficit.
Pre-administration of either scopoletin or UPEI-400 significantly decreased infarct volume in the I/R model (p < 0.05), but not in the pMCAO model of stroke.
