Sentence examples for model of smallpox from inspiring English sources
In this study we use the mousepox model of smallpox to evaluate the relationship between the magnitude of the infectious virus dose and an efficacious BCV therapy outcome when treatment is initiated concomitant with detection of ectromelia virus viral DNA (vDNA) in mouse buccal swabs.
Our analysis uses a newly developed mathematical model: a continuous-time, event-driven network simulation model of smallpox ring vaccination.
A contact pattern model of smallpox spread found that outbreaks could be contained by targeted vaccination combined with early detection without resorting to mass vaccination [ 3].
We constructed a simple network model of smallpox transmission, and addressed the question of what circumstances contribute to the success of a ring vaccination campaign designed to control smallpox.
Because none of the available models includes both network structure (with explicit contact tracing) and response logistics limited by the number of available disease control investigators [ 9], we included these features in a continuous-time event-driven network simulation model of smallpox ring vaccination.
To address this, antivirals have been developed and evaluated in animal models of smallpox and monkeypox.
But animal tests of the drug have been hampered by the fact that animal models of smallpox infection are still being developed (Science, 15 March 2002, p. 2001).
The group was charged with developing models of smallpox spread and the potential effects of several types of interventions, in several attack scenarios, to help analyze a range of options.
In this regard, MVA-BN® has been shown to confer protection in animal models of smallpox through the induction of strong Th1 adaptive as well as innate immune responses [ 3– 7].
Post-exposure immunization with MVA is an effective measure in a murine model of human smallpox.
Many studies used i.v. delivery of MPXV as a model for smallpox and to test vaccines and countermeasures [33].
