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The other is the demise of what has effectively become Britain's only viable model of regeneration, and the fact that no one seems to have a clue what might replace it.
It may be possible to file them under the heading of "cultural regeneration" in a vague way, but beyond their building, do they create a sustainable model of regeneration, of employment?
Never mind the rise of the discounters, the fall of one of the big four supermarkets, and the fact that an entire model of regeneration might have bitten the dust: she and her colleagues, she says, have heard rumours that another chain might be on its way.
The most widely used model of regeneration, sciatic nerve injury, has its inherent limitations, and there is a need for other models of injury to long nerves.
Although we used a simple model of regeneration, many previous simulation studies have used static or unreported assumptions regarding regeneration.
These aspects, together with the high degree of transparency (particularly for laboratory-reared animals), short generation time (3 months) and ease of culture and ablation, also make Ciona an ideal candidate model of regeneration.
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Yoshinari, N. & Kawakami, A. Mature and juvenile tissue models of regeneration in small fish species.
In this context, amphibian and fish provide relevant models of regeneration for studying the signals required for progenitor recruitment after lesion3.
Mechanisms assembling poly-synaptic circuits and the extent to which parallel pathways can "cross-wire" to compensate for loss of one another remain unclear and are crucial to our understanding of brain development and models of regeneration.
Studies of the naturally existing and genetically modified models of regeneration certainly enhance knowledge of the molecular and cellular mechanisms underlying regeneration.
To better understand and evaluate drivers and long-term consequences of regeneration variability, simulation models that combine statistical models of regeneration with established forest growth and yield models are useful.
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