Sentence examples for model of proliferating from inspiring English sources
We have generated conditional knockout mice to obtain NFAT5−/− T lymphocytes, which we used as a model of proliferating cells to study NFAT5-dependent responses.
Human umbilical vein endothelial cells immortalized with SV40 large/small T-antigen, a model of proliferating neovascular endothelial cells, also express TEM1/endosialin [ 23].
Here, we used them as a model of proliferating, but not yet cancerous, pancreatic cells.
We have also experimented with ODE compartment models of proliferating and dormant stem cells in the framework of a murine model of haematopoiesis under chemotherapy with fairly good results (unpublished).
Because of limited supply of synovial biopsies we first sought to investigate the functional relevance of TRPM3 expression through experiments on a FLS cell-line (HIG-82 cells), a proposed model system of proliferating FLSs in joints.
To determine whether hMSCs enhanced the proliferation of endogenous cells in an HD mouse model, the number of proliferating cells in the SVZ and striatum was assessed by injecting mice with BrdU every 12 hours for the first 7 days post-implantation, thus labeling all actively dividing cells during the first 7 days and slowly proliferating cells from days 7 30.
To model the metabolism of proliferating cells we assumed that the major biomass cell components are produced at a rate proportional to the proliferation rate.
For this example, gene expression differences were calculated by taking the average of samples pre- and post-induction (by serum withdrawal) in a human model of myocyte differentiation of proliferating cells (myoblasts) to mature myotubes [ 12].
Here we have used primary lymphocytes as a cell model to study the response of proliferating NFAT5-deficient cells to pathologic hypertonic stress conditions.
Dynamic simulation and parametric sensitivity studies are used to evaluate model behavior, including the spatial distribution of proliferating, quiescent, and dead cells for different cellular characteristics.
The same conclusion was obtained when analyzing a metabolic model accounting for the metabolic demands of proliferating cells.
