Kalluri and Delgutte (2003a,b) have investigated models of onset cells in terms of their PSTH BF tone responses and rate-level (RL) functions.
[28] When we modelled age of onset, all Mendelian models, the pure polygene model, and the pure environmental model were rejected, whereas the general model was accepted at the population level in the two high-incidence areas.
To test a theoretical model of the onset and/or exacerbation of late-life suicide ideation, incorporating consideration of risk, resiliency, and precipitating factors.
The OLETF rat is an animal model of early onset hyperphagia induced obesity, presenting multiple pre-obese characteristics during the suckling period.
Results This study reports a simple, cost-effective rodent model of rapid onset of diabetes (ROD), involving GC treatment.
For this reason, the 4-AP model has been widely used as a model of partial onset neocortical seizures for therapeutic research (Gajda et al. 2005; Lees et al. 2006; Rothman 2009).
A study in transgenic APP mice, a model of early onset AD without TAU-tangle forevealed revealed that deletion of the endogenous TAU mouse gene rescues cognitive decline without impacting plaque formation [ 73].
In addition, miR-29 is down-regulated in a model of delayed onset of aging, the Ames dwarf mouse [ 42]. miR-29 was also found to be increased during spontaneous senescence in fibroblasts [ 17].
BRFSS = Behavioral Risk Factor Surveillance System, sd = standard deviation, HS = high school, SE = standard error Table 2 provides the final adjusted parsimonious model of disability onset and fair/poor health.
In the present work we further explore the senescent phenotype of pre-hMSCs previously detected by our group, and we propose an experimental model of early onset of human aging based on the induced accumulation of prelamin A in adult human stem cells (such as hMSCs).
