Sentence examples for model of mitochondrial from inspiring English sources

These mice are considered the premier model of mitochondrial disease, given the robust similarity to Leigh syndrome.

Recent evidence shows that rapamycin administered both intraperitoneally or in the diet delays disease onset and enhances survival in the Ndufs4 null mouse model of mitochondrial encephalopathy.

Based on the first law of thermodynamics and the thermal diffusion equation, the deduced theoretical model of mitochondrial thermogenesis satisfies the Laplace equation and is a special case of the thermal diffusion equation.

MPA is designed to extract motion pattern information from the mitochondrial trajectories exported by MiTracker and to generate the statistical results based on the transient model of mitochondrial movement.

The third follow-up time of 7 days is the time point when temporary threshold shifts remained significantly approved in an animal model of mitochondrial toxin-induced hearing loss [28].

An in vitro model of mitochondrial dysfunction with subsequent oxidative stress was elaborated and utilized to study the effect of drugs, currently used for the treatment of Parkinson's disease, on pathological H2O2-evoked [3H]dopamine efflux and the formation of toxic dopamine metabolites in rat striatal slices.

We have demonstrated in thyroid oncocytoma, which constitute a model of mitochondrial-rich tumours, a high rate of PRC induction, with no disruption of mitochondrial functions [15].

As probucol was previously reported to be beneficial in a mouse model of mitochondrial-based glomerular disease caused by mutations in Mpv17 (Binder et al, 1999), we added 1% probucol to standard mouse chow (TestDiet) fed to B6. Pdss2 kd/kd missense mutant mice.

Pharmacological activation of NAD+ production has recently been used to treat mouse models of mitochondrial diseases.

In this review, we will summarize and discuss the different therapeutic interventions tested in some mouse models of mitochondrial diseases emphasizing the molecular mechanisms of action and their potential applications.

This assay will be useful for monitoring clonal expansions of mtDNA deletions and investigating the role of heteroplasmy in cell-to-cell heterogeneity in cellular models of mitochondrial disease and aging.