Sentence examples for model of meningitis from inspiring English sources

In order to obtain tissue samples for protein extraction, the same procedures as for RNA extraction were followed on the experimental model of meningitis.

In the experimental model of meningitis, clinical parameters such as clinical score and weight difference were assessed at defined time points.

Hyaluronidase has been described as a virulence factor of S. pneumoniae; the addition of hyaluronidase to an intra-nasal inoculum was necessary to cause invasive disease in an infant mouse model of meningitis [99].

Hyaluronidase mutants do not appear to be attenuated in a murine model of meningitis after intracerebral infection [100], suggesting that this degradative enzyme may be important for the bacteria to cross the mucosa or the BBB during the early stages of pathogenesis.

Similar findings were reported after intraventricular CpG-DNA injections as a model of meningitis [ 54].

The influence of CTX-M production on virulence was investigated in cell culture and a newborn mouse model of meningitis.

Further experiments using the E. coli K1 neonatal model as well as adult animal models of meningitis when testing S. pneumoniae or N. meningitidis will better determine the possible use of DXM in association with PAb or MAb F 598 in bacterial meningitis treatment as well as the general and local levels of inflammation with both treatments.

Since human cases of meningitis caused by different bacterial or fungal species are relatively uncommon in developed countries and acquisition of sufficient spectral data would require several years, a proof of principle study was performed using rat models of meningitis.

In this work, we explore the potential of fuzzy cognitive map to assist in the modeling of meningitis, as a support tool for physicians in the accurate diagnosis and treatment of the condition.

To this purpose, several therapeutic approaches have been attempted in animal models of meningitis caused by Streptococcus pneumoniae and Streptococcus agalactiae, including the use of nonbacteriolytic antibiotics, antioxidants, antagonists of excitatory amino acids, and also inhibitors of transcription factors, MMPs, caspases, or complement factors [ 17- 21, 33, 37- 41].

Although there are few clinical studies relating to the use of teicoplanin in meningitis, in a rabbit model of MRSA meningitis the antibacterial activity of vancomycin and teicoplanin was shown to be similar [ 34].