Non-slipping adhesive contact between mismatched elastic spheres: a model of adhesion mediated deformation sensor.
The chemical degradation of scaffolds with collagenases is well established, but to date this has not been correlated with an in vitro model of cell mediated scaffold degradation.
The finding that chronic high TNF-α had a slow and progressive neurodegenerative effect in the SN provides an animal model of PD mediated by the chronic expression of a single cytokine.
In a recently developed mouse model of colitis mediated by cytotoxic CD8 T cells [8], we observed that L. casei DN-114 001 exerts a protective effect on the severity of intestinal lesions and enhances the function of mucosal CD4+ FoxP3+ Treg in the colon lamina propria (Hacini-Rachinel et al, submitted).
In light of important functions of these differentially expressed miRNAs in regulating radish root development, a hypothetical model of miRNAs mediated regulation associated with taproot thickening in radish was put forward.
Inflammatory synergy between C. albicans and S. aureus has recently been reported in an acute peritoneal model of infection, mediated by the cyclooxygenase pathway and induction of an exaggerated neutrophilic response (Peters and Noverr, 2013).
Similar to its known beneficial functions during myocardial infarction, physiological activity of STAT3 in the heart plays a protective role in a model of myocarditis mediated by CVB3 infection (Lindner et al, 2012; Yajima et al, 2006).
In a model of transplantation mediated ischemia-reperfusion lung injury, partial inhibition of IKKβ activity was protective, allowing for improved graft function, decreased pulmonary edema, and diminished stromal cell apoptosis.
At a molecular level, when a model of attachment mediated by oxytocin was developed, understandings about bonding allowed more refined therapeutic approaches, including such practices as avoiding separating a mother from her newborn.
Therefore, we propose here an updated model of sepsis pathogenesis mediated by an endotoxin tolerance-mediated immune dysfunction.
