Sentence examples for model of mania from inspiring English sources

Administration of d-amphetamine (d-AMPH) is a relevant animal model of mania and it increases oxidative stress in rat brain.

This study was designed to investigate the protective effect of melatonin in a preclinical animal model of mania induced by ouabain (OUA).

Our results showing counteracting effects of lithium and rotenone in the FST model of depression and in the amphetamine-induced hyperlocomotion model of mania are in favor of an interrelationship between the mood-stabilizing effect of Li and mitochondrial function.

Based on many clinical and preclinical findings the 'vigilance regulation model of mania' postulates that an unstable regulation of wakefulness is a pathogenetic factor in both mania and Attention Deficit Hyperactivity Disorder (ADHD) and induces hyperactivity and sensation seeking as an autoregulatory attempt to stabilize wakefulness.

In this study, we investigated a novel animal model of mania induced by delivering brief stimulation pulses to the lateral hypothalamus.

An animal model of mania (induced by amphetamine; see "Sensitization models and neurotransmitters in general"), however, showed increased cytokine levels in plasma and brain, which could together with the mania-like behavior be reversed by lithium treatment (Valvassori et al. 2015).

Our results demonstrate that the DAT KD mouse line in the BPM is a consistent, reproducible model of mania-relevant behaviors.

Predictive animal models of mania: hits, misses and future directions.

Early cognitive models of mania posit that a cognitive triad consisting of unrealistically optimistic beliefs about the self, world and future may predispose vulnerable individuals to develop manic symptoms.

The LHK model differs from currently existing models of mania such as the psychomotor stimulant-induced hyperactivity model (Berggren et al. [1978]; Furukawa et al. [1975]; Jacobs and Silverstone [1986]), dopamine transporter knockdown mice (Perry et al.[2009]), CLOCK mutant mice (Roybal et al. [2007]), or the Madison mice (Scotti et al. [2011]) in three aspects.

These characteristics of behavior are similar to those observed in mouse models of mania [14] and ADHD [16].