Sentence examples for model of intoxication from inspiring English sources

This leads to a potential model of intoxication with endotoxins rather than a true model of sepsis [32].

In a post-exposure model of intoxication, FP mAb complexes gave complete protection from a lethal BoNT/A1 dose when administered within 2 hours of toxin exposure.

This, in turn, promoted a greater than 25-fold level of cellular resistance to CT. PBA-induced toxin resistance was also demonstrated in the physiological ileal loop model of intoxication.

PBA represents a promising therapeutic to prevent or possibly treat cholera because (i) it is already approved for human use; (ii) it is effective against CT at concentrations that can be attained in patients; (iii) it exhibits low nM affinity for CT/CTA1; and (iv) it inhibits CT in the physiological ileal loop model of intoxication.

Here we used the mouse oral model of intoxication to study the translocation of the native BoNT/A holotoxin, the BoNT/A complex and the recombinant HA-C.

For the first time, the role of the NAPs in BoNT/A internalization was examined in both in vivo and in vitro models of intoxication.

Although there are little data on the liver histology in models of intoxication by Te compounds, our findings are in accordance with some studies that identified vacuolization and necrosis signals in hepatocytes of rats exposed to tellurium dioxide [ 41].

Although both C. difficile toxins A and B glucosylate Rho GTPases [ 25] and are important in pathogenesis during infection [ 26, 27], most animal models of intoxication--rabbits, mouse, rats and hamsters, are more responsive to the enterotoxic effects of toxin A than toxin B [ 23, 28].

These data suggest that rotigotine, at the doses employed, significantly protected dopamine neurons from degeneration in an acute mouse model of MPTP intoxication.

In vivo, PBA effectively blocked fluid accumulation in the physiological ileal loop model of CT intoxication.

To examine the therapeutic potential of PBA as an anti-CT agent, we employed a physiological ileal loop model of CT intoxication.