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DSS is a well-known model of inflammatory bowel disease.
Upon intraperitoneal administration both compounds exhibit analgesic activity in a rodent model of inflammatory pain.
Recently, it has been developed as a model of inflammatory bowel disease, due to their similar pathologies.
Using the transgenic HLA-B27 rat model of inflammatory bowel disease (IBD), we have previously demonstrated hepatocyte growth factor's (HGF) potential to ameliorate diarrhea and decrease bowel injury.
A longer acting composite toxin, containing the protease of type E attached to BoNT/A, displays prolonged amelioration of pain symptoms in an animal model of inflammatory pain.
The present study was designed to evaluate whether NPS may produce antinociceptive effect observed in the mouse formalin test, a model of inflammatory pain.
Interleukin-10 deficient mice, a well characterized experimental model of inflammatory bowel disease, spontaneously developed a Th1 T cell-mediated colitis with many similarities to Crohn's disease.
DOR-eGFP mice were tested in the Complete Freud's Adjuvant (CFA) model of inflammatory pain [27].
Two different variations of the Complete Freund's Adjuvant (CFA) model of inflammatory pain were used.
Serum transfer arthritis (STA), is a well-characterized model of inflammatory bone loss that mimics rheumatoid arthritis [22].
TRPV1 plays an important role in inflammatory hyperalgesia and allodynia and intradermal capsaicin injection has been used extensively as a model of inflammatory pain (for review see [56]).
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