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In a rat model of infected full thickness excision wounds, treatment by CEN1 HC significantly reduced the bacterial counts of MRSA as well as P. aeruginosa, the most common pathogens in topical infections in man.
The efficacy for these compounds was evaluated in a murine BALB/c model of infected splenocytes with L. infantum.
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In the combined model of HIV infected and uninfected men, the unadjusted incidence of all fragility fractures was 2.5/1,000 person-years among HIV infected and 1.9/1,000 person-years among uninfected men (p<0.0001).
Employing a novel in vivo model of human infected erythrocyte sequestration, immunized animals were challenged with the FCR3S1.2 clone and cross-protection in terms of reduction in lung sequestration amounting to approximately 50% was demonstrated.
Initially we explored the effect of covariates on fragility fracture risk in a combined model of HIV infected and uninfected men.
Evaluation of anti-Pneumocystis spp. activities was conducted with an immunosuppressed mouse model of pneumocystosis infected with P. murina as previously described [42].
Virulence was tested in a clearance model of intravenously infected C57BL/6 mice (Pei et al., 2006).
Furthermore, in this report, we describe mouse model of wound infected with bioluminescent derivative of methicillin-resistant S. aureus (MRSA) strain (Xen31) and topical application of fulleropyrrolidine to the infected site followed by green light illumination.
A murine model of HIV infected with Cryptococcus produced reduced levels of chemokines CCL2 and CCL5, which are immune cell attractants, in comparison to non-infected mice (Leongson and Cousineau-Côté, 2013).
Additionally, a virulence study using a murine model of infection found that mice infected with A1b died significantly earlier than mice infected with A1a or A2 [ 16].
The regression model for the total number of infected in the medium transmissibility scenario had an R value of 0.9144, which is a marked improvement over the low transmissibility scenario.
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