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These new sensory receptors can also re-establish synaptic connections with afferent neurons, leading to a moderate restoration of hearing in a guinea pig model of hearing loss [8] [9].

Importantly, on an animal model of hearing loss driven by mitochondrial alterations, ER stress was suggested to have a key role.

Over 30 years ago, Plomp [ 23] proposed a model of hearing aid benefit that classed hearing impairment in terms of attenuation and distortion showing that while the hearing aids of the day could compensate well for the former by providing amplification, they were poorer at tackling the latter.

"The frog is really a fabulous model of hearing," says Narins.

This review presents a simple fundamental neurobiological model of hearing perception at a category level that incorporates principles of bottom-up signal processing together with top-down constraints of grounded cognition theories of knowledge representation.

Similar(55)

An elasto-plastic model of hear strength versus strain is also assumed to study the redistribution of the stress released by a local failure.

As well, this research now opens up the possibility of investigating cochlear mechanics in transgenic mouse models of hearing loss.

In fact, the one of the known models of hearing loss in Pendred syndrome is iron/free radical stress-mediated [ 18].

Indeed, GFI1 is also involved in the development of the inner ear hair cells [Möröy T., 2005], and its mRNA was robustly downregulated in two independent murine models of hearing loss [Hertzano et al., 2004, Lewis et al., 2009].

In mouse models of hearing loss, females lose hearing earlier than males in a strain with early-onset hearing loss comparable in timing to that in Turner syndrome females, but males lose hearing earlier in strains with the late-onset, age-related loss that corresponds to the usual situation in humans (Henry 2004).

IK developed the original model of the prediction model for hearing loss and helped to draft the manuscript.

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