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A new approach to design a dynamic model of genes with multiple autonomous regulatory modules by evolutionary computations is proposed.
For easier visualization, we included information on the presence of putative TF-binding sites and re-drew the regulatory model of genes in the starch sub-network.
The pilot project revealed surprising results, such as pervasive intragenic and intergenic transcription, new intronic and intergenic exons, overlapping transcripts, and distant transcriptional start sites, challenging the conventional model of genes and their transcription [ 1].
Thus we combine a model of genes and binding sites on a genome, that are translated into a regulatory network, with a very abstract approach to metabolic processing: processing a resource through a gene expression pattern in time.
Each time the same pairwise model of genes is found in another source, the left-hand index of the implication score for that pairwise model increases by one; each time it is found in another group from the same source, the right-hand index increases by one.
Based on a predictive model of genes under positive selection and on other genomic variations investigated, the genes MTL1, FLO1/5/9/11, CYC3, GPR1, ADH7 and ENA1-2 are strong candidates for being directly responsible for the phenotypic changes between the strains.
Similar(54)
Although the operon model has proved a useful model of gene regulation in bacteria, different regulatory mechanisms are employed in eukaryotes.
We thus design a model of gene expression.
The observed genetic structure of sampled sites conformed to a hierarchical model of gene flow.
We apply our approach to a simple model of gene expression and benchmark the performance.
The paper is concerned with periodic solutions of a model of gene regulatory system with time-varying coefficients and delays.
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CEO of Professional Science Editing for Scientists @ prosciediting.com