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Using a murine model of fragility fractures, we found that local rhTNF treatment improved fracture healing during the early phase of repair.
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When comparing adjusted models of fragility fracture risk in HIV infected and uninfected men, relationships between the covariates and fragility fracture were similar.
In a separate analysis, to test whether fragile sites are associated with a higher incidence of repeats and CpG islands we estimated a Logit model of site fragility using repeats and CpG islands as predictors.
Then, different statistical learning techniques are compared to develop surrogate models of bridge fragility using the FSI model in order to reduce the computational expense of developing fragility surfaces, or statements of failure probability conditioned on hazard intensity.
According to the coupling model (CM), the index of fragility, which can be considered as a measure of the cooperativity, can be related to the Kohlrausch Williams Watts (KWW) exponent.
Activation of the FPS, a multidisciplinary integrated model of care for secondary prevention of fragility fractures, is an effective strategy for increasing the probability that older adults at the highest risk of a subsequent fragility fracture receive BMD testing, fall and fracture risk assessment, antifracture medications, and for improving 1-year adherence to treatment.
Fragility estimated using this approach can be used as a very reliable prior estimate within Bayesian fragility models so that the posterior estimate of fragility curve can be obtained using a very few number of nonlinear time-history analyses.
To permit more quantitative examination of lysis rates, we have developed a mathematical model for osmotic fragility of infected cells based on diffusional uptake via PESAC and the two-compartment geometry of infected RBCs.
The present findings are supported by a recent theoretical report for calculated enthalpy curves with different fragilities from a model of selenium using the enthalpy landscape approach.
He does have a history of fragility.
"That was the first sign of fragility".
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