Sentence examples for model of fibrosis from inspiring English sources

It is well-known that animals can recover and regenerate in the BLM model of fibrosis when the level of injury is not too severe.

The tissue change can make women more susceptible to breast cancer, and a reliable model of fibrosis eventually could be used to screen for therapies to combat the process.

Here, we exploit recent advances in stem cell derived human intestinal organoids (HIOs) as a new human model of fibrosis in CD.

Similar results were found using a model of fibrosis associated with chronically inhaled endotoxin [31].

Another model of fibrosis involves repeated subcutaneous delivery of bleomycin [24], which results in an experiment model of systemic sclerosis characterized by increased local skin collagen deposition, as well as a subsequent increase in pulmonary collagen deposition.

Early mechanical stiffness has been described in the rat CCl4 model of fibrosis.

Further, in a model of fibrosis-associated EMT, TNFα was shown to induce transcriptional upregulation of CD44 and its subsequent pericellular interaction with hyaluronan, leading to cell-cell dissociation and cellular motility [ 10].

This is consistent with the critical importance of this cytokine in diverse models of fibrosis in various tissues.

In the current review, we contrast different in vitro models based on increasing dimensionality (2D, 2.5D and 3D), with added focus on contemporary 3D pulmonary models of fibrosis.

Dramatic increases in HA and versican have been demonstrated, in animal models of fibrosis and inflammation, in both lung tissue and bronchoalveolar lavage fluid.

Fig. 4 Overall significant metabolites from models of fibrosis, necroinflammation and steatosis.