Sentence examples for model of exacerbation from inspiring English sources
A new model of exacerbation of asthma should therefore include inducement of these IFNs to allow the discovery of different action profiles of novel drugs.
The appropriateness of a Poisson or negative binomial model of exacerbations will be confirmed by examining the residuals of the observed data fitted to the postulated models against an envelope of residuals from a set of simulated trials.
Predictive models of exacerbation are more accurate than the forced expiratory volume in one second (FEV1).
We are currently conducting studies in a mouse model of asthma exacerbation to investigate the efficacy of anti-IL-13 mAb therapy on the decline in lung function and AHR caused by exposure to HDM with concomitant viral infection.
This study contributes a new predictive model of COPD exacerbation with variables that are easily and swiftly collected.
This predictive model of acute exacerbation in COPD can be easily and quickly implemented in primary care.
The purpose of this study was to develop a model of asthma exacerbation that involves increased lung expression of such cytokines that are potential targets for pharmacological inhibition.
Our model of COPD exacerbation permits repeated lower airway sampling in treatment-naïve subjects in a manner not possible with naturally occurring exacerbations, thereby reducing variability and offering unique insights into the mechanisms of COPD exacerbations.
This finding is also in keeping with our human model of COPD RV exacerbation where increased lymphocytes in BAL were seen at 7 days after RV infection in patients with COPD compared with healthy controls [ 7] with a predominance of CD8+ T-cells [ 16].
Nuclear NF-κB p65 activation in a model of RV exacerbation of allergic airways inflammation was also assessed using a commercial kit (TransAM p65 DNA binding assay, Active Motif, La Hulpe, Belgium), using 20 µg per well of nuclear protein and the manufacturer's recommended protocol.
In conclusion, this study identifies a mouse model of asthma exacerbations harbouring several inflammatory characteristics of severe acute stages of the human disease.
