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The estimated lambdas were 0.49 and 0.63, suggesting a codominant model of effects was most likely for two genes.
Our conceptual model of effects of exposure reduction also does not address the time lag that might be required for health benefits to be achieved.
Similar to Type A questions, Type B questions (Table 2) can be addressed by establishing a P-value for the slope using a prespecified linear model of effects vs. exposure.
To test an additive model of effects on response inhibition, separate 2*2 ANCOVAS with between-subject factors "AD/HD" and "ODD/CD" and covariate "age" were computed for the main dependent variables SSRT and Stop-N200.
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An additive model of effect for the risk allele of an SNP was implemented.
We have seen that RDA is a special case of the toxicologic model of effect summation.
In all genetic analyses, an additive model of effect was used.
A similar problem exists with econometric analyses – studies by economists who often take measures of class size, or more usually pupil-teacher ratios (which is not the same thing), and develop statistical models of effects that take little account of what actually happens in school.
However, the health economic modelling of effects after follow-up is common and indeed recommended [ 14, 19] to obtain a full measurement of the effects of medical interventions.
This method facilitates adjustments for possible confounders and straightforward modeling of effect modifiers, as opposed to Edwards' model [ 10].
We fitted random effects meta-regression models of effect size on IF, COI category, and funding status, using within-study SSEs (vide supra) to weight observations.
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