Sentence examples for model of differentiation from inspiring English sources

Here, we use CD4+ T cells as a model of differentiation, mapping the activity of cell-type-specific enhancer elements in T helper 1 (Th1) and Th2 cells.

Notably, induction of mES cell differentiation led to dynamic changes in B-Myb RNA and protein expression, but the timing of change depended on the model of differentiation.

In particular, the known transcriptional mechanisms during the initial steps of OPC differentiation suggest a general de-repression model of differentiation, whereby inhibitors are repressed upon the initiation of differentiation [11].

For instance, it was recently shown that such population relationships greatly increased the rate of false positives in tests of selection based on FST which use a null distribution generated under a simple island model of differentiation [31].

Recent data suggest a model of differentiation from naïve to antigen-specific memory T cells based on the lineage markers CCR7, which is a lymph node homing receptor and the RA isoform of CD45, which is a marker expressed on naïve lymphocytes, and is re-expressed at the fully mature stage of differentiation.

PC12 cells have been extensively used as a model of differentiation.

Different models of differentiation were designed according to addition of fetal bovine serum (FBS) or knockout™ serum replacement (KoSR) to the medium of three stages.

ES cells also exhibit the capacity to contribute to a wide range of well-defined cell types when using several in vitro models of differentiation.

In addition, both models of differentiation could only be related to very simple demographic models and thus departure from the true demographic history might also affect the PPP-value distribution.

There are indeed models of differentiation which are able to describe some of them [3] [10] [11]; they make use of a continuum description and, in part because of computational limitations, are bound to take into account the contributions of only few genes.

The work on MEL cells, as well as on other models of differentiation, is directed at understanding the molecular basis of leukemogenic transformation and cellular differentiation.