Sentence examples for model of degeneration from inspiring English sources

The rabbit annular puncture model of degeneration is among the most widely used models of intervertebral disc (IVD) degeneration.

Interestingly, however, Sakai and colleagues demonstrated promising results in a rabbit model of degeneration where they showed enhanced matrix formation [ 33] following injection of MSCs embedded in atelocollagen.

Imai et al [ 15] use this in a rabbit model of chemonucleolysis, whilst it has also been suggested to be useful for a model of degeneration in mice[ 16].

A direct link between CXCL12/CXCR4 upregulation and loss of dopaminergic neurons was provided in an animal model of degeneration of the nigrostriatal system following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration, a well-recognized model of PD [ 18].

11 27 Our results also do not support models of degeneration with age, 12 as clusters do not differ by age.

Using the broad-spectrum CSPG antibody CS-56 we have seen very different patterns of expression in different models of degeneration (Barber et al., 2013).

Thus, although the study of animals that develop degeneration spontaneously [ 61, 62] and of injury models of degeneration [ 63, 64] have provided some insight into the degenerative processes, most information on aetiology of disc degeneration to date has come from human studies.

Two factors that change to variable extents in different models of degeneration, namely the integrity of the OLM and the extent of recipient retinal gliosis, have been found to play key roles in determining the success of transplanted donor cell migration and integration (Barber et al., 2013; Kinouchi et al., 2003; Pearson et al., 2010; West et al., 2008).

To examine the effects of OSM on photoreceptor degeneration, we used the heterozygous S334ter-3 rass as a model of retinal degeneration with rapid degeneration of rod photoreceptors [18].

Sirt1 may serve as a downstream effector of increased NAD biosynthesis and delay axonal degeneration in a mouse model of Wallerian degeneration [ 69].

Furthermore, as our understanding of disc degeneration advances, a reproducible animal model of disc degeneration will enable controlled testing of therapeutic strategies.