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Apoptosis is an active model of cell death that regulates cell number [9], [19], [20].
To date, few studies have reported a preventive effect of ubiquinone analogs in a model of cell death.
These data support the pore-forming model of the mode of action of Cry toxins and contradict the model of cell death induced by the interaction with cadherin receptor and subsequent induction of signal transduction pathway.
We also examined whether ephrinB3 could improve cell survival in non-caspase, glutamate-induced excitotoxicity model of cell death.
Therefore, enhanced cell death in Parg −/− ES cells does not follow the typical energy failure model of cell death.
In the UV irradiation model of cell death in this cell type, JNK pathway activation appears to be mediated by kinases other than MLKs.
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Parasagittal Eaat4 expressing stripes of Purkinje cells are preserved in ischemic models of cell death [25], [42].
Can computational models of cell death incorporate multiple sources of cell-to-cell variability?
How can this noise in gene expression be incorporated into models of cell death?
In parallel, research has been focused on the connection of signalling between the different models of cell death.
The cleavage of chromatin into oligonucleosomal fragments, which form the characteristic apoptotic DNA ladder, has been documented in numerous models of cell death.
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