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By exploring the geometry of contact distribution at protein-protein interfaces, we provide an improved model of binding energy.
The risk assessment model of binding mode is established through using AHP and fuzzy comprehensive evaluation method.
On the basis of the model of binding isotherm assumed, zonal elution was used to investigate the binding interaction of the receptor with terbutaline and salbutamol.
The absorbance decreasing effect can be used as an evidence that there exists an interaction model of binding between metal ions and DNA base pairs or nucleotide, i.e., metal ions can coordinate into DNA base pairs and bind to nucleic acids [19, 20].
The experimental results proved that the π → π* transitions of DNA at 260 nm showed an intensity decrease with increasing doses of nano-anatase TiO2, which supports the notion that there exists an interaction model of binding, i.e., a strong π-stacking interaction between Ti4+ and DNA base pairs [19, 20].
We obtained a rough model of binding of DLAPSQ or STIVYS with the insulin receptor, which provides the powerful theoretical support for designing the minimal insulin mimetic peptide with agonist activity, making it possible to develop oral small molecular hypoglycemic drugs.
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Our focus for the benchmark is methods which search for TFBS using known models of binding sites, not ab initio TFBS discovery.
For this reason, more complex models of binding specificity have been developed.
Anisotropy data were fit using equations for seven distinct models of binding.
Nevertheless, parsimony-generated models of binding site evolution tend to overfit so that ReXSpecies also suffers from that overfitting.
All TRANSFAC mammalian matrix models of binding sites [ 28]were mapped using the Match™ program with minFP profiles for optimized thresholds of the matrix models [ 29].
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