Sentence examples for model of allergy from inspiring English sources
A similar correlation between certain allergic responses and increased IFN-γ expression has been reported in human clinical studies of allergy; this pig model of allergy may be indicative of potential probiotic modulation of allergic lung disease in humans.
Using this pig model of allergy we demonstrated the ability to induce allergic manifestations of immediate skin hypersensitivity and allergic lung disease in pigs, as well as a reduction in the severity of both of these allergic manifestations via probiotic intervention.
In this swine model of allergy, the allergic response was induced by immunizing pigs with an extract from the roundworm Ascaris suum containing allergens known to elicit strong Th2 responses [23] that had been mixed with alum, an adjuvant classically used to further enhance the intensity of Th2 responses.
The relevance of ITK was validated in a mouse model of allergy.
The main objective of this study was to investigate the allergy-promoting capacity of four different CNF samples in an injection and an airway mouse model of allergy.
It is also possible to perform functional studies of candidate genes in activated T cells, or in a well-defined mouse model of allergy.
Elevated IL-9 production and Th9 differentiation have been demonstrated in mouse models of allergy and melanoma [ 54, 55].
Prior to clinical development of the T cell epitope peptide therapies, murine models of allergy were developed to validate the strategy and further explore mechanisms.
Passive cutaneous anaphylaxis (PCA) is the gold standard method to measure allergen-specific IgE antibody levels in mouse models of allergy.
Impairment of immune tolerance has been shown to augment disease in various models of allergy and/or autoimmunity, including diabetes onset in NOD mice [ 18, 19], collagen-induced arthritis [ 20, 21], and experimental colitis [ 22].
Many studies reporting successful peptide immunotherapy in murine models of allergy demonstrated that administration of immunodominant T cell epitope peptides of major allergens induced tolerance not only to those peptides but also to purified allergen and whole allergen extracts 30– 30.
