Sentence examples for model of alcoholic from inspiring English sources

We hereby took advantage of a transgenic mouse model with the cardiac-specific overexpression of ADH, which mimics an accelerated alcoholic cardiomyopathy model of alcoholic cardiomyopathy [15].

However, in animals it is very difficult to establish an experimental model of alcoholic liver disease.

It should be noted that we cannot exclude that bortezomib acted through increased expression of antioxidant enzymes as has been reported for a rat model of alcoholic liver disease (Bardag-Gorce et al., 2011).

Recent observations by Petrasek and colleagues (2012) in a mouse model of alcoholic hepatitis support significant involvement of another important cytokine, IL-1β which IL-1β whichn rhasmatoid arolestin and autoimmune disorheumatoidlcohol-induced inflarthritis

One of these models is the Tsukamoto-French rat model of alcoholic liver disease (Tsukamoto et al. 1985), in which male Wistar rats were fed a liquid diet containing a constant amount of alcohol (13 g/kg/day) for 30 days using an intragastric feeding tube.

In a model termed the 'cyclosporin A model of alcoholic chronic pancreatitis' by Gukovsky et al. addition of CsA to caerulein in rats that were additionally fed with ethanol led to a decrease of pancreatic parenchyma by approximately 86% and a severe impairment of the functional reserve.

The caspase-3 inhibitors showed promising potential in several animal models of alcoholic liver diseases, hepatitis B and C virus infection (Kunstle et al., 1997), myocardial infarction and infarct size in stroke (Cheng et al., 1998; Yaoita et al., 2000), sepsis (Hotchkiss and Karl, 2003), neuronal death and in spinal cord injury (Springer et al., 1999).

These findings are similar to the reported influence of diet in rodent models of alcoholic steatohepatitis (ASH).

Oxidative stress and endotoxin (lipopolysaccharide (LPS)) are commonly elevated in the blood of alcoholics and in certain animal models of alcoholic liver disease [ 17].

Experimental models of alcoholic pancreatitis have shown that lipopolysaccharide (LPS) exacerbates the development of alcoholic AP and that repeated exposure to LPS results in fibrogenesis and chronic pancreatitis (CP).

Previous studies in experimental models of alcoholic fatty liver disease have shown induction of a 'hypermetabolic state' and enhanced tissue hypoxia in response to increased O2 uptake coupled to ethanol oxidation [ 37].