Sentence examples for model of adoptive from inspiring English sources

We review recent studies that have applied in vivo RNAi screens in T cells to examine genes that regulate T cell differentiation during viral infection, and that control their accumulation in tumors in a model of adoptive T cell therapy.

To test this, we employed a well-characterized tumor model of adoptive transfer immunotherapy.

Thus, reactivated memory CD8 T cells were more potent than resting memory cells in this model of adoptive T cell therapy.

We tested the capacity of VT680 to label and remain in cells, to keep cells alive and functional, and to report on biodistribution and T cell behavior in a tumor model of adoptive transfer immunotherapy in vivo using FMT and IVM, and ex vivo by flow cytometry.

In a model of adoptive cellular therapy we established E1A-MEF and E1A-Cox2-MEF fibyosubcutaneoussubcutaneous injection of 1 × 10 cancer cells in the flank region of immunocompromised NOD/SCID mice.

Moreover, in a murine model of adoptive transfer of autoimmune diabetes, antigen-specific T cell responses and disease incidence were decreased by the systemic delivery of miR-29b, while in vitro, exosomes derived from beta-cells presented specific miRNA expression profiles, including miR-29b.

Therefore, progression of events leading to xenograft rejection in a mouse model deprived of adoptive immune function may simplify the identification of the requirements for tumor rejection and, more broadly, those necessary for TSD [ 2].

To test if pro-inflammatory and regulatory T cells migrate via a similar molecular mechanism, we analyzed the expression of different adhesion molecules, as well as the composition of infiltrating T cells in an in vivo model of MS, adoptive transfer experimental autoimmune encephalomyelitis in rats.

In contrast, it has been shown with the use of an EAE model that adoptive transfer of IL-23-induced, IL-17-producing effector cells induces disease, whereas IL-12-induced, IFN-γ-producing effector cells do not [ 18].

To determine whether oral administration of L. casei could induce a similar conditioning of naive CD8+ T cells in lymphoid organs, we set up a model of CHS induced by adoptive transfer of CD8+ T cells into T cell deficient CD3ε°/° mice.

During allergic contact hypersensitivity in a mouse model of allergic contact dermatitis, adoptive transfer of Treg cells has been shown to suppress immune cell infiltration and the resulting local swelling response (Ring et al., 2009) whereas depletion of Treg cells causes enhanced and prolonged skin inflammation (Tomura et al., 2010).