Sentence examples for model of activation from inspiring English sources

The classic model of activation of telomerase, for which activity has been found in most cancers including cutaneous malignant melanoma (CMM), dictates that enzyme activity is generated by pathological reactivation of telomerase in telomerase-negative somatic cells.

The results support a model of activation that is consistent with most of the biochemical observations.

A conceptually similar mechanism was proposed for class-C GPCRs as the "peptide-linker model" of activation (Margeta-Mitrovic et al., 2001), prior to the availability of structural information for dimerization.

Together, these results support a model of activation of PhoB in which phosphorylation promotes dimerization via the α4-β5-α5 facenhances enhances DNA binding and thus the ability of PhoB to regulate transcription.

In our subsequent work, we are focusing on dealing with the binding effect (defined as occupancy by Bolouri et al [23] and Istrail et al [24]) of transcription factors on the activation of cis-acting sites to generalise the simple on/off model of activation.

They detected 16 proteins showing differences based on the model of activation [ 65].

We focus on their physiological functions, structure and regulation, and describe current models of activation mechanisms.

Genetic modelling of activation of the Wnt signalling pathway in the intestine has been made possible by the generation of Apc mutant mice that recapitulate human colonic carcinogenesis.

Among the several subunits of the Kv family which are expressed by microglia in different models of activation, Kv1.1, Kv1.2, Kv1.3, Kv1.5, Kv1.6 and Kv3.1 could in theory mediate Kdr currents in hippocampal microglia (see introduction for references).

This is essentially the opposite mechanism to that proposed by Kavran et al. Further work is needed to resolve these conflicting models of activation.

Model studies of activation of thiolate nucleophiles by Zn2+ have demonstrated increased reactivity with an increased number of thiolate ligands.