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While the three-dimensional structure of LCAT is not yet known, a partial model now exists that facilitates the study of structure function relationships of the native enzyme, and of natural and engineered mutants.
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A number of process models now exist that estimate carbon and water vapor exchange across a broad array of vegetation.
As a number of excellent models now exist, the next 5 10 years will ascertain whether these models will predict response of human cancer to intervention.
For many ADME properties, models now exist which provide reasonably good predictive quality and can be deployed to aid medicinal chemists in drug discovery projects.
With a projector, of which models now exist that can be attached to your smartphone, and adequate amounts of e-skin and foresight, a similar phenomena could take place on any surface― even from the comfort of one's home.
Appreciation for the importance of Allee effects in rare and endangered taxa is increasing, and a number of theoretical models now exist to predict extinction boundaries within species or populations for a variety of demographic characteristics and mating systems [9], [12].
Several conceptual models now exist that describe these factors [ 12, 13, 16- 19].
Supporting this, several models now exist showing that the microenvironment can have a profound effect on breast cancer progression.
Indeed several models now exist of disease transmission in the presence of low or undetectable levels of PrPd.
Evidence shows that giving women information about the likely outcome can manage expectations and reduce anxiety, 12 and scoring systems and models now exist that give an accurate prediction regarding the likelihood of miscarriage.
Several other mutant SOD1 mouse models now exist that also model ALS; these models all have slightly different pathologies, including time to onset of symptoms and death (e.g. Bruijn et al., 1997; Jonsson et al., 2006; Nicholson et al., 2000).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com