Sentence examples for model notch from inspiring English sources

Unlike Lewis, we shall also model Notch and NICD explicitly.

Both point and line defects are considered to model notches or line cracks and delaminations in the plate.

Furthermore, no clear effectors of cell-cycle regulation have been identified in the wing, although in some leukaemic cells and mouse breast tumour models Notch directly regulates genes involved in the G1 to S-phase transition, including D-type cyclins (Joshi et al, 2009; Ling et al, 2010).

These include genes that are known to affect developmental processes in other vertebrate models: notch (1,2,3,4), nrg1, bmp1, wnt4, ctnna1, btnna1, dkk1, axin 1, nrg1, fgf10, sirt (1,2,5,6), stats (1, 2, 3, 5, 6), sema4f, tf, sfrp (1,2,5), rara, rarg, rxr, pdgf, acvrI (IB, IIA, IIB), bmprI, bmprII, smad (1, 2, 4, 5, 7, 9), efna1, ntn1, slit2, slit3, robo1, and robo2.

We use a simple lateral inhibition model for Notch signaling that consists of Notch receptors, Delta ligands and bound Notch/Delta complexes [ 85- 87].

These interactions indicate a simple model for Notch target-gene regulation that could explain the precision of gene activation elicited by Notch signaling in different developmental fate decisions.

The model of Notch cleavage that has developed from the accumulated evidence of many different laboratories has Notch being cleaved in its extracellular domain by Furin (S1) as it traffics to the cell surface.

Based on the proposed correction method integrated with constitutive equations using Garud's hardening model, a notch stress-strain estimation methodology is developed to calculate the local elastic-plastic stress-strain responses at the notch area.

In the present paper, a model for notch fatigue damage evaluation in the case of an arbitrary multiaxial loading history is proposed by using an endurance function which quantifies the damage accumulation in the material up to the final failure.

Based on the comparison between the experimental and computed strain histories, the elasto-plastic stress strain model estimated notch strains with reasonable accuracy using linear-elastic FE stress histories.

These results support a model wherein Notch signaling in bone marrow normally acts to maintain a pool of mesenchymal progenitors by suppressing osteoblast differentiation.