Sentence examples for model mutations that from inspiring English sources

Under this model, mutations that created improved matches to the uptake bias were, over evolutionary time, more often transmitted to other cells by this biased transformation.

According to this model, mutations that disrupt the secondary structure of the distal part of the MRE β-loop would compromise its interaction with a substrate.

Under our model, mutations that occur along the branches separating the target haplotype and the template haplotype will be incorrectly imputed.

Indeed, supporting this model mutations that prolong anaphase (yku70∆) and mutations that weaken the nuclear diffusion barrier without prolonging anaphase (bud6∆) both affect circle retention.

Consistent with this vectorial folding model, mutations that impair the folding of C-terminal segments of two different passenger domains significantly reduce the efficiency of secretion (Peterson et al., 2010; Renn et al., 2012).

In agreement with this model, several mutations that make BvgS insensitive to negative modulating signals map to the linker and PAS domains [43], [44].

All four RP models represent mutations that are similar to the ones found in certain cohorts of patients.

Furthermore, in C. intestinalis, CpG depletion was best modelled by mutations that were dependent on the upstream base (eg. C,G→A; Figure  3 and data not shown).

Interestingly, the hallmark phenotype of all long-lived mouse models containing mutations that induce GH/IGF-1 deficiency or resistance, is their enhanced insulin sensitivity [ 6].

Previous investigation and modelling of mutations that create dinucleotide frequency biases have typically concentrated specifically on CpG and its under-representation in mammalian genomes.

However, gene modification in the embryo might not fully recapitulate gene manipulation in the adult to model somatic gene mutations that lead to the development of sporadic cancers.