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For both sexes, disability trajectories were best represented by a four-group model (model parameters shown in Supplementary Table 1).
Power analysis of smaller multivariate models can be performed but it requires synthetic data based on an assumed model, model parameters and expected covariate distributions.
We simulated 25 bootstrap matrices with Mesquite and, for each matrix, constructed a maximum likelihood tree (general-time-reversible model; model parameters, gamma shape correction and proportion of invariable sites being estimated from each matrix; rearrangements limited to 1,000).
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Model selection was based on the objective function value (OFV, the lowest value corresponds to the best model), model parameter uncertainty, and graphic analysis using Xpose 4 [35] implemented in software R 2.7.1.
For each model parameter, we calculated the Akaike Information Criterion (AIC) of both the full model (model parameter = CG + PD + MT + year of publication) and each of the four linear models including only three of the four explanatory factors.
In these slip models, model parameters (e.g., total slip, rupture time, and rise time) have been attributed to each sub-fault.
The construction of the conditional probability (likelihood function) for general model-based inference problems is discussed in detail to systematically manage uncertainties from mechanism modeling, model parameters, and measurements.
Seven articles contained models, model parameters, or experimental data on the inactivation of ricin in food (see Table 1).
For example, when inferring positive selection, it would be more accurate to base inferences on all possible/plausible alignments, models, model parameters, and trees than to base them on one or a subset of possible alignments.
Estimates for the simple random-effects one-parameter model (Model 1) are shown in Fig. 1B.
The final mathematical model (Model 6; model equations, parameter values, and notation see Methods and Additional file 1) was derived step by step (see Figure 3), keeping the model structure (components and interactions) as simple as possible.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com