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Xu, Q. et al. A mouse model mimicking human first night effect for the evaluation of hypnotics.
The GL-induced peak and timing of glycogen increase in the muscle are also consistent with previous studies5,6,7,8, indicating the physiological validity of our rat model mimicking human GL.
This study was designed to examine the effect of ethanol on rat heart tissue with an experimental model mimicking human binge drinking.
An animal model mimicking human cardiac circulation may be of great help.
Over the past decade, many laboratories tried to develop a mouse model mimicking human nephrotic syndrome (Table 1).
These findings raised the interest of using a "modified" rodent model mimicking human bone conditions to investigate various bone diseases.
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Therefore, the development of mouse models mimicking human immunodeficiency (SCID and OS) allowed us to investigate the pathogenesis of immunological disorders.
We expect MEMRI to be promising for future applications in longitudinal studies on development, aging, or regeneration of CNS projections in mouse models mimicking human CNS pathologies.
Materials and methods We designed a rat study to investigate lithium-induced encephalopathy and correlate its severity to plasma, erythrocyte, cerebrospinal fluid and brain lithium concentrations previously determined in rat models mimicking human poisoning patterns.
Obviously, in most animal models mimicking human PBC, AMAs against PDC-E2 play a crucial role.
Multiple kinds of mouse models, mimicking human skeleton diseases caused by missense mutations in FGFs and FGFRs, have been established by knock-in/out and transgenic technologies.
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