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The results may suggest the relevance of our study in A498 model mice to human studies partly although further studies to clarify whether our results are actually general or not are necessary.
Here, we subjected FNDI model mice to intermittent water deprivation (WD) in order to promote the phenotypes.
IL-32 induced the differentiation of CD4+ T cells of RA model mice to Th17 cells and promoted IL-17 production.
The author includes data from several different published reports to analyze and compare behavioral results in CGG KI premutation model mice to similar tests done in Fmr1 KO animals.
We use both primary cell culture and two different SMA model mice to demonstrate that reduced levels of Smn lead to a profound disruption in the expression of myogenic genes.
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However, we observed that αB-crystallin levels in brain lysates decreased in an age-dependent manner in transgenic AD model mice compared to non-transgenic littermates.
12, 13 Here, we report three novel cancer model mice predisposed to neuroendocrine tumors.
These results demonstrate that TSA can increase myogenic proteins early in SMA model mice prior to overt motor neuron pathology.
Moreover, decreased secretion of Aβ has been observed over time in cultured primary neurons derived from AD model mice, leading to intracellular Aβ accumulation [ 86].
For the postmenopausal model, mice were subjected to ovariectomy 1 week prior to tumor cell inoculation.
In the neuroblastoma xenograft model, mice were allowed to consume only water for 48 hours prior to etoposide treatment.
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