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In this model, mice are exposed to novelty in an unfamiliar open space setting with no safe alternative.
In this model, mice are infected several times with the oral pathogen P. gingivalis by oral gavage, resulting in local inflammation and CD4+ T-cell-mediated bone loss.16 P. gingivalis derived peptides were presented mainly by iDCs to both CD4+ and CD8+ T cells.
In this model, mice are immuno-compromised by cyclophosphamide treatment.
In this model, mice are immunocompetent and the endpoint measurement is not mice survival but rather tissue colonization by the infection agent.
In this model, mice are subjected to unilateral hindlimb plaster casting.
In this model mice are injected with serum (NTS) from a sheep immunized with mouse glomeruli.
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We set a humane endpoint in the tumour model; mice were sacrificed when the tumour volume reached 2000, mm3, which has been approved by the Animal Ethics Committee of Keio University.
For cytokine studies in the sepsis model, mice were sacrificed by decapitation 12 h and 24 h after bacterial inoculation to harvest blood.
And while the intestinal lining of the autism model mice was too thin, the lining in the SSRI and SERTKO mice was too thick.
In the C57BL/6-to-BALB/c model, mice were lethally irradiated and then rescued with an allogeneic donor BM. 2 × 106 GMSCs or fibroblast cells were injected the same day as acute GVHD was induced.
The model mice were orally treated with DHA (10 mg/kg) at 12 days after birth and their bilirubin levels were measured at 14 days after birth, 48 hours after the treatment.
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CEO of Professional Science Editing for Scientists @ prosciediting.com