Sentence examples for model mediated by from inspiring English sources

The results presented in this study identify a novel role of CCL25/CCR9 interactions in the pathogenesis of a well-established acute colitis model mediated by oral administration of DSS.

However, prior to this study, no work has been presented on CCL25/CCR9 interactions in an experimental acute colitis mouse model mediated by DSS exposure.

In vivo experiments made in MyMRKO mice, but in the hypertensive model mediated by angiotensin II/L-NAME, did not show protection to develop hypertension but presented reduced signs of aortic fibrosis and hypertrophy.

Although, some authors still support sperm-binding model mediated by ZP3 [ 2, 3, 59], such model has been called into questions and is gradually replaced by a three-dimensional ZP structure model [ 11- 13].

Subsequent studies made in a hypertensive mouse model mediated by deoxycorticosterone acetate- (DOCA-) salt in wild-type mice showed an increase in blood pressure in the chronic phase of the disease (4 8 weeks) and in the percentage of collagen deposition in perivascular and interstitial heart wall [ 26].

This arthritis model, mediated by autoantibodies against the ubiquitous enzyme glucose-6-phosphate isomerase (GPI), demonstrates important similarities to human RA including symmetric joint involvement, chronicity, a distal-to-proximal gradient of joint involvement, and histological features including synovial infiltrates, pannus, and erosions of cartilage and bone [ 66].

To enable more comprehensive analysis of signalling in endothelial permeability, there is a need to develop an expanded ODE model that covers the signalling mediated by multiple mediators, particularly thrombin, histamine and VEGF.

We specified an adjusted mediation model to assess the direct, indirect (mediated by economic capital) and total (direct plus indirect) effects of socio-cultural capital on maternal health-seeking behaviours [ 17, 18].

The single neuron model is a simple leaky integrate-and-fire (LIF) model with the inclusion of a synaptic current mediated by network firing events, and a model of (I_{text{h}}) based on a single gating variable.

Specifically, this would mean the addition of two feedback mechanisms to the mathematical model, one mediated by UmuDC, and the other mediated by Pol V.

Therefore, we hypothesize that the dysglycemia observed in this animal model following fetal and neonatal nicotine exposure is likely mediated by pancreatic mitochondrial defects.