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Scientists can model many aspects of pedestrian behaviour, but religious fervour is a step too far.
NGF deprivation has been widely used as an in vitro model to induce axon degeneration and is thought to model many aspects of developmental pruning [ 1].
Wfs1 knockout mice accurately model many aspects of Wolfram syndrome, including type 1 diabetes, retinal degeneration, and impaired behavioral responses to stress (Luuk et al., 2008; Kato et al., 2008).
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AirTran models many aspects of its operations after Southwest, including quick airplane turnaround times, which help to keep costs down.
Exceptions do exist, however; for example, the B9d1-null mouse models many aspects of human MKS (Dowdle et al., 2011).
This mutant models many aspects of ATD, but is difficult to analyse owing to high rates of lethality.
Brothers et al. also developed the zebrafish larva as a transparent vertebrate model of disseminated candidiasis, showing that the infection model reproduces many aspects of candidemia in mammalian hosts [ 10].
As noted in previous simulation modeling [7], many aspects of this delay have a significant chance component, making the delay a random variable.
The model supports many aspects of the classic loop-axis/radial loop models pioneered by Laemmli et al.: the presence of an array of loops of around 80 kb as had been observed by electron microscopy, e.g., [ 111, 121].
While this mouse model mimics many aspects of human pathology, including metastatic dissemination, it is not attractive as a preclinical model because of the severity of skin-related problems due to cytokeratin 14 (K14) promoter driven Cre recombinase (K14cre) expression in multiple epithelial tissues.
Despite structural support for the quartet model, many regulatory aspects of this model have yet to be identified.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com