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Interestingly enough, not a single Mercedes-Benz model makes this list.
The continuous trajectory of the protein in our model makes this calculation impractical.
The model makes this assumption by using the same rate class distribution for spatial and temporal rate variation.
Although our model makes this a precept, we also note that in doing so, we open it to empirical research.
When a single virus particle infects a cell, the virus can be considered a haploid organism, and indeed the quasispecies model makes this assumption.
The recent finding that leucocidin ED specifically targets neutrophils and is an important virulence determinate in a murine bloodstream model makes this a likely candidate to play a key role in CC130 pathogenicity (Alonzo et al, 2012).
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Good solubility, moderate bioavailability, and promising in vivo activity in xenograft model made this series of compounds interesting starting points to design new potent HDAC inhibitors.
It is possible that we would have seen a stronger synergy in our tumor challenge studies with additional boosts or a different immunization schedule; however, the very aggressive nature of this tumor model made this difficult to evaluate.
Parametric modeling makes this generating task easy and less time consuming because basic features and relations between them are in constant fashion for a specific product.
The chronic progressive nature of dopaminergic neurodegeneration, which is absent in most existing PD models, makes this new model invaluable for the study of mechanisms of PD progression.
In fact, the nature of molecular medicine research, oriented towards pathophysiological processes, systems and models makes this field one of the spearheads of the rapid evolution in life sciences.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com