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In our sample, decreasing ΔSOFA, ΔPCT and ΔCRP were significantly predictive of survival in univariable analysis, but the multivariable regression model maintained only ΔPCT and ΔCRP as independent predictors for survival, as early as in D4.
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Analyzing leptin as dependent variable in a multivariate model, significant correlation was maintained only between leptin and metastasis (β = 0.40; p <0.001).
After a logistic regression model was applied, this relationship was maintained only with a secondary school level of educational attainment.
By using empirically derived estimates of male and female fitness to quantify the magnitude of intralocus sexual conflict at this locus [ 23, 24], we find that polymorphism in resistance is maintained over a wide range of values, which contrasts with previous models [ 15– 18] where genetic variation was maintained only in limited parameter range.
It is worth noting, that in our models stable subpopulations of A and B type cells are maintained only if the phenotypic switch is reversible.
Only geopolymer matrices with suitable fracture toughness, as defined by the micromechanics design model, maintained the desirable tensile ductility of the developed fly ash-based EGC.
Given that our mixed co-culture model was maintained using only DMEM and collagen, we suspect that the BMSCs or the matrix molecules released by the BMSCs may act as substitutes for these types of matrices in three-dimensional culture.
When the same analysis was done for each group, the general model only maintained the significance in the DD group (F 3,32) = 4.224; p = 0.010), explaining 21.8% of the variance, where the only significant variable was daily consumption of coffee (see Table 5).
Our 3D model not only maintained cell viability but also preserved the typical osteogenic phenotype of PCa PDX cells.
These results were robust to sensitivity analysis excluding all time-invariant variables from the final model and only maintaining time trend and meteorology (data not shown).
Most bistable models only maintain their switch-like behavior in a limited parameter range.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com