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The model is structurally calibrated for 2011.
The model is structurally estimated using the British Household Panel Survey (BHPS).
Taken together, the proposed enhanced homogenized surface-based FE model is structurally more accurate than density-only models.
We show that while the model is structurally identifiable, it is practically unidentifiable under a range of human and mosquito time series measurement scenarios.
Uncertainty and sensitivity analysis is conducted to explore the behavior of the model, because the model is structurally complex and the values of many input parameters are estimated with a high degree of uncertainty.
The 3D model is structurally closest to the endo-1,4-β-d-glucanase from Pseudomonas putida KT2440 (PDB ID: 4Q2B) with a template modeling score (TM-score) of 0.90 and an alignment coverage of 0.90.
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Initially, the previously built [14] UNAcP model was structurally aligned with the crystal structure of pyrophosphorylase with PDB code 1JV1 [16], whose active site was preserved, as shown by the structural alignment [23].
Using MacPyMOL (http://www.pymol.org), the EFL model was structurally aligned with the crystal structure of EF-Tu on the ribosome (PDB IDs 2WRN and 2WRO) [ 22] in order to indicate likely ribosome and aa-tRNA binding surfaces.
To generate a model of the dimer, two copies of the best-scoring Pro3 model were structurally aligned (using PyMol) to chains A & E of PDB structure 2RCY, the most closely related homolog.
The model was structurally validated using the ProSA-web error-detection software and the Ramachandran plot.
Thus the parameters in this model are structurally non-identifiable when x20 = x30 = 0.
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