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Instead, an elastic degrading material model is activated for the failed layer to simulate the post-ultimate response.
The contact model is activated during the contact phase which is defined by both geometrical and force-dependent conditions.
(The two models, Lakoff has said, are personified by Arnold Schwarzenegger on one side and Oprah Winfrey on the other). Most voters, Lakoff suggests, carry some part of both parental frames in the synapses of their brains; which model is "activated" -- that is, which they can better relate to -- depends on the language that politicians use and the story that they tell.
Therefore, Re θc is the point where the model is activated to match both Re θt and F length.
The final output of the module is the level of caspase-3, which (in the model) is activated by Bax (or Bak), but also auto-catalytically, which renders the apoptotic decision irreversible.
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For higher credibility and accuracy, quantum-mechanical models are activated and empirical material parameters are employed from the existing literature.
The oncogenic K-ras alleles in these models are activated somatically in one (KrasLA1) and conditionally in the other (KrasLSL) (5, 7).
The neurons in the hidden layer in these models are activated not only by the input neurons but also by the neighboring neurons in the layer; consequently, the dynamics of these neuron activities are not determined solely by the inputs but can autonomously change even in the absence of inputs, as in the case of our model.
We further showed, when the models were activated by transient signal, memory (total time taken by the cascade output to reach its unstimulated level after removal of signal) of a cascade was determined by the specific designs of interaction among its kinases and phosphatases.
Given that, in the model, RSK is activated by MAPK, this combination of activity-levels seems unlikely to occur.
These data suggest that, in this model, Bax is activated early in the process and that its increase is sustained till 12h after kainic acid injection which is the time of first appearance of caspase-3 activation and TUNEL positivity, and that SMases contribute to increases in ceramide levels during and after status epilepticus.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com