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Industry needs integration of product specific terminology and product generic data schemas for man-model interaction and data exchange in next generation of CADCAM systems to improve product realization.

The timing and synchronization information and importance of modeling interactions and their implications are described.

Methods for modeling interactions and dose-response also are reviewed, and references to more detailed literature are provided.

When included in the same model, interaction between obesity and sex was not significant.

In this model, interaction between anxiety and optimism was significant for the Social Functioning dimension (p = 0.0021).

In this model, interaction between anxiety and optimism was significant for the SF dimension (p = 0.0021).

Comparison between the model with interaction and the model without interaction showed that resources are less idle and lower acuity patients are processed slower because of consultation time.

In a second model, interaction effects between altitude and land allocation zoning were added (Table 1).

In a second model, interaction effects between altitude and land allocation zoning were added (Table  1).

Guidelines for Principle 1   1A - Be age-appropriate   1B - Encourage and model interaction   1C - Use special effects wisely  .

† For the sensitivity/specificity model: interaction between the variable and the reference standard (see Additional file 1) ‡ For the likelihood ratios model: interaction between the variable and the diagnostic test (see Additional file 1).

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