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This situation is frequently modeled through a Cox-proportional hazards model including covariates, some of which are under the control of the experimenter.
Change from baseline was analyzed using a linear mixed effects model including covariates of treatment, visit, treatment by visit interaction, stratification factors (region and migraine prophylaxis medication status), and baseline value.
We conclude that when the data are generated from a hidden regression model, including covariates in POPS increases the performances of the program.
For each SNP, a one-degree of freedom likelihood ratio test comparing the model including covariates age and gender with the model including covariates age, gender and SNP genotype was performed.
The combined model, including covariates, SNP-GRSS, and 16p12.3 deletion accounted for 11.5% of phenotypic variance in BMI (3.2% from genetic effects).
To estimate the net predictive performance of the adenoma attributes this model was contrasted with the model including covariates alone and the incremental Receiver operating characteristic-area under the curve for the contrast was reported (Table 4).
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The final model including covariate effects is shown in Fig. 2.
The first model includes covariates related to background and work related characteristics, early life course variables, attitudes and values.
The baseline model included covariates and income poverty.
Final model included covariates that were statistically significant.
The multivariable model included covariates found to be statistically significant (p<0.05) on unadjusted analysis as well as those deemed a priori to be most biologically salient to CIN incidence and progression.
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