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As this was an exploratory study, and subjects were their own controls, a linear mixed model in procedure Mixed in SAS (System 9.1, SAS Institute Inc ,Cary, North Carolina, USA) was used to analyse the continuous variables, clinical performance and individual experiences.
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The mdx mouse has been used as an experimental model in procedures involving the use of stem cells (Gussoni et al., 1999 [ 28]; McKinney-Freeman et al., 2002 [ 29]; Corbel et al. [ 30]; Fukada et al., 2001[ 31]; Hagiwara et al., 2006 [ 32]), showing that this model has been useful for DMD studies.
Moreover, in the swap analysis, the MCC achieved by our model in training procedure (MCC = 0.343) was equal to that achieved in validation procedure, indicating the robust model performance.
Parameters of the model in the procedure are calibrated by field and laboratory tests.
The generalized mixed model in GLIMMIX procedure in SAS v9.2 [ 33] was used to fit the multilevel model.
Thus the effect of grain size distribution is thought to be of importance in both the interpretation of experimental data in terms of the grain model and in procedures used for deducing kinetic parameters from experimental measurements.
The identification technique incorporates the equivalent linear damper model in the estimation procedure.
These compounds were selected to exemplify the usage of a rigorously built and validated pharmacophore model in the selection procedure.
For this, we included 25 of the 44 parameters of the model in the optimization procedure.
The best model (M4) is highlighted in bold and all differences in AIC among models ΔAIC) are computed relative to M4. WAIC are the statistical weights of each model in the model averaging procedure we used.
The analysis of variance was carried out using the generalized linear model (GLM) procedure in SAS.
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