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The current study was performed using the murine C17.2 neural progenitor cell line, a commonly used model in developmental neurobiology71 and neurotoxicology70 research.
A new model in developmental biology, for example, was discovered by an artificial intelligence engine that went over just 16 experiments published in the past.
Zebrafish are an increasingly important model in developmental toxicology, pharmacology and chemical effects on disease.
The zebrafish, Danio rerio, is currently the most popular fish model in developmental and genomic analyses and a genome sequencing project is currently underway [ 4].
The application of the zebrafish model in developmental biology research has resulted in a plethora of background literature, as well as the incorporation of the species into genetic and toxicology research.
A dominant model in developmental and clinical research, which we refer to as the cumulative risk model, proposes that it is the accumulation of risk exposures across setting and time that is most likely to lead to disturbance.
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With its invariant cell lineage, easy genetics and small genome, the nematode Caenorhabditis elegans has emerged as one of the prime models in developmental biology over the last 50 years.
The combination of marker-assisted analysis of population structure and screening of phenotypic classes is central not only in shaping models in developmental biology but also in evolutionary genetics of populations.
The recent discovery that even simple organisms like fish and social insects are capable of numerical abilities similar to primates may pave the way to the use of new animal models in developmental research.
Although alternative pregnancy assays have been developed, biologists continue to use Xenopus as a model organism in developmental biology because their embryos are large and easy to manipulate, they are readily obtainable, and can easily be kept in the laboratory.
hES cells constitute a valuable model system in developmental studies and in the search for new regenerative therapies.
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