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The new hybrid model introduces model improvements by considering the proliferative state of stem cells and enabling a cell cycle-dependent effect of chemotherapy.
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Secondly, we investigate model improvement by including also vector gradient data.
There is no significant evidence of geoid model improvement by GOCE-based GGMs over EGM2008 in Hokkaido, Central Honshu and Kyushu regions.
The total model improvement by adding the set of interactions is tested with the appropriate degrees of freedom.
Models with age and region were compared with a model only containing school-level random effect to assess model improvement by their inclusion.
In order to evaluate the statistical significance of model improvement by sequential addition of fixed effects, the maximum likelihood method and likelihood ratio tests were applied.
In addition, all data from the database or user-files can now be analysed by pair-wise joint mortality modelling and detection of significant model improvement by separately fitted single parameters, i.e. detection of significantly different optimal model parameters.
The effects of the business model improvements proposed by SBB Cargo were integrated directly into the model (improved efficiency of the wagon usage by shorter round-trip times, decreasing transhipment costs in hinterland terminals).
To measure survival model improvements offered by SES indices, area under the curve (AUC) values from time-adjusted receiver operator characteristic curves were generated from covariate-adjusted Cox regression models [25], using nearest neighbour kernel smoothing [26].
In addition, model improvements are expected by incorporating other impacting factors, for example comedication, aggregation, excipient in the formulation, or patient immune status.
Ancestral reconstructions can be improved both by data selection and by model improvements.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com