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In summary, our structural model identifies many of the dynamic subunits, not revealed by other structural techniques, that provide an important additional layer of complexity to the quaternary structure of human U1 snRNP.
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These survival-prediction models identified many factors significantly associated with post-PMV survival (Table 2 and Additional file 2; all ORs were adjusted for all other covariates).
It is a model that identifies many millions of Americans as the enemy, dismissing them in fundamental ways from our national life.
Future prediction models will identify many more women with a lifetime risk of more than 30% – classified as 'high risk' according to NICE National Institute for Health and Clinical Excellencee, 2006).
Studies in experimental models have identified many quantitative trait loci (QTLs) that show a significant association with arthritis susceptibility and severity [ 3- 6].
Although the simple model identified the majority of features identified by the stress model, it also identified many more features in total than the stress model.
Studies using HD model mice have identified many genes whose expression is altered by mutant huntingtin (4– 7).
Genetic screens in simple model organisms have identified many of the key components of the conserved signal transduction pathways that are oncogenic when misregulated.
This genetic dissection in the model legumes has identified many genes required for nodulation: components of the symbiotic signaling (Sym) pathway (recently reviewed by [ 8- 12]), genes functioning in regulation of nodule number [ 13- 16], bacterial infection [ 17- 19], bacterial differentiation [ 20], maintenance [ 21, 22] and nutrient transport [ 23, 24].
Using designed β-hairpins or other β-sheet model systems, researchers have identified many factors that can significantly change the folding rate, stability or strand registry of β-sheets, such as charge interactions (Smith and Regan, 1995), beta propensity (Phillips et al., 2005) and β-sheet surface complementarity (Liang et al., 2008).
However, in the past 15 years, since the link between FRDA and FXN was identified, many models of FRDA have been generated that have enabled advances in understanding the function of frataxin, the pathophysiology of the disease, and some of the mechanisms implicated in GAA-based silencing and instability.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com