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More specifically, using nematodes as model hosts for understanding infection requires greater understanding of how nematode physiology and behavior can be affected by bacteria.
Plants have also been utilized as simple surrogate model hosts for studying host-pathogen interactions as an alternative to traditional animal pathogenesis models [17], [18].
The nematode Caenorhabditis elegans is one of the popular model hosts for the study of the evolutionarily conserved mechanism of microbial pathogenesis and innate immunity.
The larvae of the greater wax moth Galleria mellonella are now established as model hosts for pathogens that infect insects or humans.
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Dionne, M.S., Ghori, N. & Schneider, D.S. Drosophila melanogaster is a genetically tractable model host for Mycobacterium marinum.
D'Argenio, D.A., Gallagher, L.A., Berg, C.A. & Manoil, C. Drosophila as a model host for Pseudomonas aeruginosa infection.
van der Sar, A. M. et al. Zebrafish embryos as a model host for the real time analysis of Salmonella typhimurium infections.
We report here the establishment of the fruit fly Drosophila melanogaster as a new model host for the exploration of L. monocytogenes pathogenesis and host response to infection.
Chicken embryos as alternative model host for fungal pathogens were already described in 1939 by Moore [16].
A broader goal of these studies was to enhance the use of C. elegans as a model host for the study of pathogenesis in animals.
Further, the genome sequence will facilitate the development of H. orenii as a model host for cloning and expression of thermohalophilic proteins.
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