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Two studies using a mouse model have reported elevated ABR thresholds after chronic, low-dose exposure to MeHg (Chuu et al. 2001; Huang et al. 2008).
Other groups using the same model have reported similar findings of reduced perfused capillary density and increased heterogeneity in intestinal mucosa [ 5- 7].
In fact, previous studies using the same model have reported increases in iNOS mRNA (Juarranz et al., 2005) and plasma NOx (Sakaguchi et al., 2004).
Because previous studies using the high-dose MIA rat model have reported the involvement of subchondral bone as early as two weeks after injection [ 21], two weeks was chosen as the early time point in this study.
Other studies using an acute LPS rat model have reported that IL-10 levels were higher in lung tissue, peritoneal fluid, and serum of rats treated with melatonin, although the doses of melatonin given were approximately three-fold higher than in our study.
Previous studies using the high-dose MIA rat model have reported the presence of acute inflammation characterized by expansion of the synovial membrane with infiltrating macrophages, neutrophils and plasma cells in the rat's knee joint one day after injection which resolved by day seven [ 19, 28].
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Previous study with CCR9 knockout mouse model has reported no adverse side effects of CCR9 gene ablation, besides the reduction in the γδ IELs which are characterized by their CCR9+ phenotype (Wurbel et al, 2001).
An apoE (apolipoprotien E -deficient mousE -deficientreported that a loss of TLR4 and its adaptor mouseule model (myeloid differentiation factor 88) decreased thassevereportedathatosclerosis and alossed atherofcleroTLR4plande formatits [ 22].
In the low-salinity zone of the San Francisco Estuary mass balance calculations and models have reported that clams (especially the invasive Potamocorbula amurensis) suppress phytoplankton blooms.
However, few studies based on finite-element (FE) models have reported that the presence of FRP in shear-strengthened RC beams limits strain in the transverse-steel (e.g., Chen et al. 2010).
However, recent studies in healthy and pathological animal models have reported neural dynamics that do not match with this view of the GPe as a relay in the BG circuit.
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